Archive for September, 2008

What to eat? how much to eat?

Michael Pollen’s new book, In Defense of Food: An Eater’s Manifesto argues for simplification of dietary habits in this world of complicated food products. This is what he has to say in a nutshell:

What to Eat?
Don’t eat anything your great-grandmother wouldn’t recognize as food (non-dairy creamer?)
Avoid food products with ingredients that are unfamiliar, unpronounceable, more than 5 in number, or that contain high-fructose corn syrup (none of these is necessarily bad in itself, but they raise red flags).
Avoid food products that make health claims. Broccoli and tomatoes are silent. If a product needs to crow about being healthy, chances are it isn’t.
Shop the periphery of the supermarket where the fresh food resides
Get out of the supermarket and shop at a farmers’ market
Eat mostly plants: more leaves than seeds
Choose quality over quantity
Eat until you’re no longer hungry, not until you’re full.
Sit down to real meals with other people; eat slowly and mindfully; enjoy your food

Or put simply in the authors own words: “Eat food. Not too much. Mostly Plants.”
Reference: Science Based Medicine
So what does “Not too much” food mean?
Does it mean that we should eat till our appetite is satisfied. Or does it mean that we should eat till we no longer feel hungry. There is an excellent article in Scientific American which explains that eating behavior is influenced by two mechanisms in the human brain:

Hypothalamic center which controls the need to eat
Higher cortical centers mediated by dopamine reward system which controls the desire to eat

The answer to “How much food should we eat” seems clear enough.

The desire to eat can override the need to eat, leading people to consume tasty foods even when they’re not hungry. The inability to forego these rewarding aspects of food intake override long-term homeostatic control, contributing to obesity.

Reference: Scientific American
Books by Michael Pollen

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Eat For Goals! - UEFA, The World Heart Federation And The European Commission Come Together To Tackle Childhood Obesity

The Union of European Football Associations (UEFA) and the World Heart Federation, with the support of the European Commission, came together at the British School of Brussels to launch the children’s cookery book, Eat for Goals! Through the book the message that a healthy lifestyle is als

Warfarin Linked To Increased Bleeding In Brain

A new study shows that people who take the commonly used blood thinning drug warfarin may have larger amounts of bleeding in the brain and increased risk of death if they suffer a hemorrhagic stroke. The study is published in the September 30, 2008, print issue of Neurology®, the medical journal of the American Academy of Neurology. Warfarin is commonly prescribed to prevent blood clotting.

Statins Not Linked To Higher Risk Of ALS Says FDA

A new analysis by the US Food and Drug Administration (FDA) of data from over 40 clinical trials did not show a link between statins, drugs used to lower cholesterol, and higher risk of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease often referred to as “Lou Gehrig’s Disease”. The FDA said there is no need to change prescribing practice.

New Field Of Metabolomics Yields Exciting Antiviral Treatment Approach

Viruses dramatically increase cellular metabolism, and existing anti-obesity drugs may represent a new way to block these metabolic changes and inhibit viral infection, according to a study published in the journal Nature Biotechnology. Metabolism refers to all the reactions by which living things break down nutrients to produce energy, along with those by which they rebuild broken-down nutrients into complex molecules (e.g. DNA).

Behavioral Modification Programs Help Obese Children Manage Their Weight

Obese school-age kids and teens can lose weight or prevent further weight gain if they participate in medium- to high-intensity behavioral management programs, according to a new report released today by HHS’ Agency for Healthcare Research and Quality. Children in the medium- to high-intensity behavioral management programs studied met for more than 25 hours, usually once or twice a week, for 6 months to 12 months.

ThromboGenics Announces Promising Results Of MITI IV Phase II Trial In The Treatment Of Acute Stroke With Microplasmin

ThromboGenics NV (Euronext Brussels: THR), a biotechnology company focused on novel therapies for eye disease, vascular disease and cancer, announces positive results from its MITI IV Phase II trial to evaluate the safety and preliminary efficacy of microplasmin when administered intravenously to acute stroke patients. The trial showed that microplasmin was generally well tolerated and also provided some interesting preliminary efficacy data.

FDA: No Lou Gehrig's disease risk with statins (Reuters)

Reuters - An analysis of dozens of studies found the widely used statin cholesterol drugs do not increase the risk of Lou Gehrig's disease, U.S. health officials said on Monday.

Statins Can Prevent Premature Ageing Of Arteries

New research from the UK found that statins, normally prescribed for lowering cholesterol and reducing heart attack risk, can stop arteries ageing prematurely in patients with advanced heart disease.

Obesity-related Ill Health Still On The Rise In Europe

Alarming reports on the risks and costs of obesity, and the ensuing health consequences, the number of obese people in Europe is still on the rise. Eucomed believes that proper nutrition and sufficient exercise can be a major help in the fight against obesity. In some people however, only a surgical procedure can yield positive short- and long-term results. “Still today, the idea of undergoing surgery to counter obesity is surrounded by scepticism and controversy.